Topical Therapies for Eczema Sandra Lawton Nurse Consultant Dermatology [email protected] Treatment: stepped approach to management Use a stepped approach for managing atopic eczema:
tailor treatment step to severity use emollients all the time step treatment up or down as necessary Provide: information on how to recognise flares instructions and treatments for managing flares Treatment:
stepped approach to management Mild atopic eczema Moderate atopic eczema Severe atopic eczema Emollients
Bandages Bandages Phototherapy Systemic therapy Case Study
Age 5 School Statement Sleep Terrible Repeat Prescriptions+++++ Chaotic routine Admission
Emollients Which one is best??? Soap Substitutes Bath Oils Shower Moisturisers Others
Effects of Emollients Soothe Anti-inflammatory Soften Anti-pruritic
Hydrate Steroid-sparing effect Protect Additives
Emollients may have ingredients added : preservatives such as chlorocresol and parabens) antiseptics such as benzalkonium chloride, antipruritics such as lauromacrogols). These added ingredients can act as irritants or allergens and provoke sensitisation or an immune response. Humectants
Humectants are substances introduced into the stratum corneum to increase its water-holding capacity. The mode of action involves the active movement of water from the dermis to the epidermis. Humectants include propylene glycol, lactic acid, urea and glycerol. Some creams and lotions contain a mixture of occlusive and humectant substances the humectant draws water into the epidermis, while the occlusive element ensures that it is trapped there.
Bathing Bathing is useful for cleansing the skin, removing scale and previous topical therapies. Bathing will also hydrate the skin and this is an ideal time to apply an
emollient providing a lipid film, which prevents water evaporation from the epidermis. Emollient bath additives Aveeno bath oil Balneum bath oil
Adequate Supplies Availability Demonstrate Other Issues for patients Does it smell? Texture and consistency how easy it is to apply?
Does it make the skin too shiny? Does it make clothes greasy? Packaging tubes and pumps are popular. Can it be used as a soap substitute? Is it so greasy that it spoils school work? Does it sting? Treatment: emollients
Emollients should be: unperfumed used every day prescribed in large quantities (250500 g/week) easily available to use at nursery, pre-school or school. Cradle Cap
Hobbies Head Lice Treatment: topical corticosteroids Potency should be tailored to severity:
mild potency for face and neck, except for 35 days of moderate potency for severe flares moderate or potent preparations for short periods only for flares in vulnerable sites do not use very potent preparations in children without specialist dermatological advice Potency
Hydrocortisone butyrate (Locoid) Very potent Clobetasol propionate 0.05% (Dermovate) Application Age
Disease severity Amount : Finger tip method v tube size Surface area Site
Frequency : Occlusion 1v 2 x daily. Other treatments Patient preference
Vehicle Bursts Atopic Eczema Atopic Eczema
Local side-effects spread and worsening of untreated infection; thinning of the skin irreversible striae and telangiectasia; contact dermatitis; perioral dermatitis acne at the site of application in some patients
Tachyphylaxis Loss of effect Depends upon: Usage frequency Potency Is reversible Recommend change of topical steroids
Topical Calcineurin Inhibitors Second line treatment for atopic eczema Pimecrolimus cream (Elidel) Tacrolimus 0.03% or 0.1% ointment (Protopic) Effective, and increasingly used Used to prevent flares Initiated by physician with interest in dermatology Unknown long term risk of skin cancer
Bandaging and suits To improve emollient effect Wet/dry garments Young infants with very dry skin To cover areas to stop scratching Impregnated bandages eg ichthopaste/steripaste Older children with limb or finger eczema
Education and adherence to therapy Spend time educating children and their parents or carers about atopic eczema and its treatment. Provide written and verbal information with practical demonstrations about: how much of the treatments to use
how often to apply treatments when and how to step treatment up or down how to treat infected atopic eczema. NICE Guideline Atopic eczema in children Management of atopic eczema in children from birth up to the age of 12
years www.nice.org.uk/CG057 www.nottinghameczema.org. uk
www.odesi.ca 22 J. Fry, S. Mowers, Séance de formation de base de l'IDD, le 31 mai 2011 Personnes-ressources Pour obtenir de plus amples renseignements : Jane Fry [email protected] Susan Mowers [email protected] * * * L'Université Carleton, qui est responsable au...
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